Publications 2021

A novel smaller β-defensin-derived peptide is active against multidrug-resistant bacterial strains.

Colicchio R, Nigro E, Colavita I, Pagliuca C, Di Maro S, Tomassi S, Scaglione E, Carbone F, Carriero MV, Matarese G, Daniele A, Cosconati S, Pessi A, Salvatore F, Salvatore P.
FASEB J. 2021 Dec;35(12):e22026. doi: 10.1096/fj.202002330RR.

CD4 + T-Cell Activation Prompts Suppressive Function by Extracellular Vesicle-Associated MicroRNAs.

Di Silvestre D, Garavelli S, Procaccini C, Prattichizzo F, Passignani G, De Rosa V, Mauri P, Matarese G, de Candia P.
Front Cell Dev Biol. 2021 Oct 27;9:753884. doi: 10.3389/fcell.2021.753884.

CD8+ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis.

Feizi N, Focaccetti C, Pacella I, Tucci G, Rossi A, Costanza M, Pedotti R, Sidney J, Sette A, La Rocca C, Procaccini C, Matarese G, Barnaba V, Piconese S.
Cell Death Dis. 2021 Oct 29;12(11):1026. doi: 10.1038/s41419-021-04310-6.

Reimagining an immunological dogma.

de Candia P, Matarese G.
Nat Immunol. 2021 Oct 18. doi: 10.1038/s41590-021-01046-5.

16S rRNA of Mucosal Colon Microbiome and CCL2 Circulating Levels Are Potential Biomarkers in Colorectal Cancer.

Nardelli C, Granata I, Nunziato M, Setaro M, Carbone F, Zulli C, Pilone V, Capoluongo ED, De Palma GD, Corcione F, Matarese G, Salvatore F, Sacchetti L.
Int J Mol Sci. 2021 Oct 4;22(19):10747. doi: 10.3390/ijms221910747.

Effect of time and titer in convalescent plasma therapy for COVID-19.

de Candia P, Prattichizzo F, Garavelli S, La Grotta R, De Rosa A, Pontarelli A, Parrella R, Ceriello A, Matarese G.
iScience. 2021 Jul 22:102898. doi: 10.1016/j.isci.2021.102898.

Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation.

Mollo N, Esposito M, Aurilia M, Scognamiglio R, Accarino R, Bonfiglio F, Cicatiello R, Charalambous M, Procaccini C, Micillo T, Genesio R, Calì G, Secondo A, Paladino S, Matarese G, Vita G, Conti A, Nitsch L, Izzo A.
Biology (Basel). 2021 Jun 30;10(7):609. doi: 10.3390/biology10070609.

Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential.

Procaccini C, Garavelli S, Carbone F, Di Silvestre D, La Rocca C, Greco D, Colamatteo A, Lepore MT, Russo C, De Rosa G, ......., Brescia Morra V, Vella D, Galgani M, Mottola M, Zuccarelli B, Lanzillo R, Maniscalco GT, Centonze D, de Candia P, Matarese G.
Immunity. 2021 May 11:S1074-7613(21)00176-X. doi: 10.1016/j.immuni.2021.04.014.

Metabolomics, Lipidomics, and Immunometabolism.

Carbone F, Bruzzaniti S, Fusco C, Colamatteo A, Micillo T, De Candia P, Bonacina F, Norata GD, Matarese G.
Methods Mol Biol. 2021;2285:319-328. doi: 10.1007/978-1-0716-1311-5_24.

The pleiotropic roles of leptin in metabolism, immunity, and cancer.

de Candia P, Prattichizzo F, Garavelli S, Alviggi C, La Cava A, Matarese G.
J Exp Med. 2021 May 3;218(5):e20191593. doi: 10.1084/jem.20191593.

Estimating asymptomatic SARS-CoV-2 infections in a geographic area of low disease incidence.

Caturano V, Manti B, Carbone F, Lasorsa VA, Colicchio R, Capasso M, Leonardi A, Matarese G, Russo T, Salvatore P.
BMC Infect Dis. 2021 Apr 15;21(1):350. doi: 10.1186/s12879-021-06054-2.

Different Susceptibility of T and B Cells to Cladribine Depends On Their Levels of Deoxycytidine Kinase Activity Linked to Activation Status.

Carlini F, Ivaldi F, Gualandi F, Boschert U, Centonze D, Matarese G, Salvetti M, Kerlero de Rosbo N, Uccelli A.
J Neuroimmune Pharmacol. 2021 Apr 14. doi: 10.1007/s11481-021-09994-3.

Serum levels of SARS-CoV-2 nucleocapsid antigen associate with inflammatory status and disease severity in COVID-19 patients.

Perna F, Bruzzaniti S, Piemonte E, Maddaloni V, Atripaldi L, Sale S, Sanduzzi A, Nicastro C, Pepe N, Bifulco M, Matarese G, Galgani M, Atripaldi L.
Clin Immunol. 2021 Apr 2:108720. doi: 10.1016/j.clim.2021.108720.

Novel acquisitions in cell immunometabolism.

Norata G, Matarese G
Mol Aspects Med. 2021 Feb 4:100945. doi: 10.1016/j.mam.2021.100945.

Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis.

Palma C, La Rocca C, Gigantino V, Aquino G, Piccaro G, Di Silvestre D, Brambilla F, Rossi R, Bonacina F, Lepore MT, Audano M, Mitro N, Botti G, Bruzzaniti S, Fusco C, Procaccini C, De Rosa V, Galgani M, Alviggi C, Puca A, Grassi F, ....Mauri P, Netea MG, de Candia P, Matarese G.
Cell Metab. 2021 Jan 4:S1550-4131(20)30671-9. doi: 10.1016/j.cmet.2020.12.016.

Trained immunity, tolerance, priming and differentiation: distinct immunological processes.

Divangahi M, .... Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, ..., van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG.
Nat Immunol. 2021 Jan;22(1):2-6. doi: 10.1038/s41590-020-00845-6.

T Cells: Warriors of SARS-CoV-2 Infection

de Candia P, Prattichizzo F, Garavelli S, Matarese G.
Trends Immunol. 2021 Jan;42(1):18-30. doi: 10.1016/j.it.2020.11.002.

CD31 Positive-Extracellular Vesicles from Patients with Type 2 Diabetes Shuttle a miRNA Signature Associated with Cardiovascular Complications.

Prattichizzo F, De Nigris V, Sabbatinelli J, Giuliani A, Castaño C, Párrizas M, Crespo I, Grimaldi A, Baranzini N, Spiga R, Mancuso E, Rippo MR, Procopio AD, Novials A, Bonfigli AR, Garavelli S, La Sala L, Matarese G, de Candia P, Olivieri F, Ceriello A
Diabetes. 2021 Jan;70(1):240-254. doi: 10.2337/db20-0199.